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1

PREDICTION OF THE THERAPEUTIC DOSE FOR BENZODIAZEPINE ANXIOLYTICS BASED ON RECEPTOR OCCUPANCY THEORY

KIYOMI ITO, AKIKO ASAKURA, YASUHIKO YAMADA, KOUICHI NAKAMURA, YASUFUMI SAWADA, TATSUJI IGA

Journal:

Biopharmaceutics & Drug Disposition

Year:

1997

Language:

english

File:

PDF, 156 KB

english, 1997

2

Coronary neovascularity: A possible sign of new and growing mural thrombus

Tai Nakamura, Osamu Yamanaka, Yasumasa Fujiwara, Morihiro Honda, Tatsuji Kanoh, Hiroshi Yamaguchi

Journal:

Catheterization and Cardiovascular Interventions

Year:

1993

Language:

english

File:

PDF, 260 KB

english, 1993

3

Analysis of Epoxyeicosatrienoic and Monohydroxyeicosatetraenoic Acids Esterified to Phospholipids in Human Red Blood Cells by Electrospray Tandem Mass Spectrometry

Nakamura, Tatsuji, Bratton, Donna L., Murphy, Robert C.

Journal:

Journal of Mass Spectrometry

Year:

1997

Language:

english

File:

PDF, 396 KB

english, 1997

4

The Effects of Indomethacin Spray on the Pain of Stomatitis in the Patients for Hematopoietic Stem Cell Transplantation

Takako Nakamura, Takao Aoyama, Yoshitsugu Yanagihara, Yasuhiko Yamada, Akemi Miyoshi, Yoshinobu Kanda, Hisamaru Hirai, Toshirou Furukawa, Tatsuji Iga

Journal:

Year:

2004

File:

PDF, 52 KB

2004

5

Motor nerve endings in extraocular muscles

Tatsuji Namba, Toshio Nakamura, Akira Takahashi, David Grob

Journal:

The Journal of Comparative Neurology

Year:

1968

Language:

english

File:

PDF, 858 KB

english, 1968

6

Hepatic tumors induced by carbon tetrachloride in transgenic mice carrying a human c-H-ras proto-oncogene without mutations

Satoshi Tsunematsu, Hidetsugu Saito, Tatehiro Kagawa, Toshio Morizane, Jun-Ichi Hata, Tatsuya Nakamura, Hiromasa Ishii, Masaharu Tsuchiya, Tatsuji Nomura, Motoya Katsuki

Journal:

International Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 1007 KB

english, 1994

7

Transplantation of galectin-1-expressing human neural stem cells into the injured spinal cord of adult common marmosets

Junichi Yamane, Masaya Nakamura, Akio Iwanami, Masanori Sakaguchi, Hiroyuki Katoh, Masayuki Yamada, Suketaka Momoshima, Sachiyo Miyao, Ken Ishii, Norikazu Tamaoki, Tatsuji Nomura, Hirotaka James Okano

Journal:

Journal of Neuroscience Research

Year:

2010

Language:

english

File:

PDF, 2.67 MB

english, 2010

8

Occurrence of Oxidized Metabolites of Arachidonic Acid Esterified to Phospholipids in Murine Lung Tissue

Tatsuji Nakamura, Peter M. Henson, Robert C. Murphy

Journal:

Analytical Biochemistry

Year:

1998

Language:

english

File:

PDF, 181 KB

english, 1998

9

High-speed solubility screening assay using ultra-performance liquid chromatography/mass spectrometry in drug discovery

Taro Yamashita, Yukifumi Dohta, Tatsuji Nakamura, Takehiro Fukami

Journal:

Journal of Chromatography A

Year:

2008

Language:

english

File:

PDF, 283 KB

english, 2008

10

Oxidation of glycerophospholipids from biological membranes by reactive oxygen species: liquid chromatographic–mass spectrometric analysis of eicosanoid products

Robert C Murphy, Nona Khaselev, Tatsuji Nakamura, Lisa M Hall

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1999

Language:

english

File:

PDF, 444 KB

english, 1999

11

Prilocaine induces apoptosis in osteoblastic cells

Keiko Nakamura, Hirofumi Kido, Yasuhiro Morimoto, Hiroyuki Morimoto, Shigeru Kobayashi, Masao Morikawa, Tatsuji Haneji

Journal:

Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Year:

1999

Language:

english

File:

PDF, 1.03 MB

english, 1999

12

Isolation and characterization of dendritic cells from common marmosets for preclinical cell therapy studies

Shigeki Ohta, Yoko Ueda, Masae Yaguchi, Yumi Matsuzaki, Masaya Nakamura, Yoshiaki Toyama, Yoshikuni Tanioka, Norikazu Tamaoki, Tatsuji Nomura, Hideyuki Okano, Yutaka Kawakami, Masahiro Toda

Journal:

Year:

2008

Language:

english

File:

PDF, 394 KB

english, 2008

13

Differences in the clinical characteristics of Pneumocystis jirovecii pneumonia in immunocompromized patients with and without HIV infection

Tatsuji ENOMOTO, Arata AZUMA, Ayumi KOHNO, Kazuyo KANEKO, Hitoshi SAITO, Minako KAMETAKA, Jiro USUKI, Akihiko GEMMA, Shoji KUDOH, Seiichi NAKAMURA

Journal:

Year:

2010

Language:

english

File:

PDF, 140 KB

english, 2010

14

Specific Inhibitors of Vacuolar H+-ATPase Trigger Apoptotic Cell Death of Osteoclasts

Nobuo Okahashi, Ichiro Nakamura, Eijiro Jimi, Masanori Koide, Tatsuo Suda, Tatsuji Nishihara

Journal:

Journal of Bone and Mineral Research

Year:

1997

Language:

english

File:

PDF, 627 KB

english, 1997

15

Analysis of Nonlinear Hepatic Clearance of a Cyclopentapeptide, BQ-123, with the Multiple Indicator Dilution Method Using the Dispersion Model

Akihiro Hisaka, Tatsuji Nakamura, Yuichi Sugiyama

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.09 MB

1999

16

Prediction of the therapeutic dose for β-stimulants based on preclinical data: Application of oral dosage forms and aerosols to asthmatic patients

Kiyomi Ito, Naoko Yajima, Hisakazu Ohtani, Yasuhiko Yamada, Kouichi Nakamura, Yasufumi Sawada, Tatsuji Iga

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1993

Language:

english

File:

PDF, 519 KB

english, 1993

17

Classification of benzodiazepine hypnotics in humans based on receptor occupancy theory

Kiyomi Ito, Yasuhiko Yamada, Kouichi Nakamura, Yasufumi Sawada, Tatsuji Iga

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1993

Language:

english

File:

PDF, 512 KB

english, 1993

18

Profiling of arachidonic acid metabolites in rabbit platelets by radio gas chromatography

Kazuki Akira, Tatsuji Nakamura, Yoshihiko Shinohara, Shigeo Baba

Journal:

Year:

1993

Language:

english

File:

PDF, 471 KB

english, 1993

19

Estimation and optimization of the peak capacity of one-dimensional gradient high performance liquid chromatography using a long monolithic silica capillary column

Kanta Horie, Yoshiaki Sato, Takayuki Kimura, Tatsuji Nakamura, Yasushi Ishihama, Yoshiya Oda, Tohru Ikegami, Nobuo Tanaka

Journal:

Journal of Chromatography A

Year:

2012

Language:

english

File:

PDF, 1.54 MB

english, 2012

20

The Role of Activin Type I Receptors in Activin A-Induced Growth Arrest and Apoptosis in Mouse B-Cell Hybridoma Cells

Osamu Hashimoto, Kenji Yamato, Takeyoshi Koseki, Masahiro Ohguchi, Akira Ishisaki, Hiroki Shoji, Takanori Nakamura, Yoshihiro Hayashi, Hiromu Sugino, Tatsuji Nishihara

Journal:

Cellular Signalling

Year:

1998

Language:

english

File:

PDF, 437 KB

english, 1998

21

A System for LogD Screening of New Drug Candidates Using a Water-Plug Injection Method and Automated Liquid Handler

Yamashita, Taro, Nishimura, Ikuko, Nakamura, Tatsuji, Fukami, Takehiro

Journal:

Journal of the Association for Laboratory Automation

Year:

2009

Language:

english

File:

PDF, 348 KB

english, 2009

22

Transplantation of dendritic cells promotes functional recovery from spinal cord injury in common marmoset

Masae Yaguchi, Masanao Tabuse, Shigeki Ohta, Kozo Ohkusu-Tsukada, Tamaki Takeuchi, Junichi Yamane, Hiroyuki Katoh, Masaya Nakamura, Yumi Matsuzaki, Masayuki Yamada, Toshio Itoh, Tatsuji Nomura, Yoshia

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 1.40 MB

english, 2009

23

High prevalence of the hepatitis C virus infection among the inpatients of schizophrenia and psychoactive substance abuse in Japan

Yu Nakamura, Motoasa Koh, Eiji Miyoshi, Osamu Ida, Masayuki Morikawa, Akihiro Tokuyama, Tatsuji Nagano, Yoshiharu Honda, Junzo Iida, Kunya Yamamoto, Naoki Minami, Akinori Kasahara, Motoharu Hirai, Nor

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

2004

Language:

english

File:

PDF, 272 KB

english, 2004

24

Identification of membrane-type receptor for bile acids (M-BAR)

Takaharu Maruyama, Yasuhisa Miyamoto, Takao Nakamura, Yoshitaka Tamai, Hiromasa Okada, Eiji Sugiyama, Tatsuji Nakamura, Hiraku Itadani, Kenichi Tanaka

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 292 KB

english, 2002

25

Quantitative Profiling of Polar Cationic Metabolites in Human Cerebrospinal Fluid by Reversed-Phase Nanoliquid Chromatography/Mass Spectrometry

Myint, Khin Than, Aoshima, Ken, Tanaka, Satoshi, Nakamura, Tatsuji, Oda, Yoshiya

Journal:

Analytical Chemistry

Year:

2009

Language:

english

File:

PDF, 1.83 MB

english, 2009

26

Quantitative and Wide-Ranging Profiling of Phospholipids in Human Plasma by Two-dimensional Liquid Chromatography/Mass Spectrometry

Sato, Yoshiaki, Nakamura, Tatsuji, Aoshima, Ken, Oda, Yoshiya

Journal:

Analytical Chemistry

Year:

2010

Language:

english

File:

PDF, 1.14 MB

english, 2010

27

Ethylenediaminetetraacetic Acid Increases Identification Rate of Phosphoproteomics in Real Biological Samples

Nakamura, Tatsuji, Myint, Khin Than, Oda, Yoshiya

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 853 KB

english, 2010

28

A System for LogD Screening of 96-Well Plates Using a Water-Plug Aspiration/Injection Method Combined with High-Performance Liquid Chromatography−Mass Spectrometry

Dohta, Yukifumi, Yamashita, Taro, Horiike, Satomi, Nakamura, Tatsuji, Fukami, Takehiro

Journal:

Analytical Chemistry

Year:

2007

Language:

english

File:

PDF, 216 KB

english, 2007

29

Evaluation of Comprehensive Multidimensional Separations Using Reversed-Phase, Reversed-Phase Liquid Chromatography/Mass Spectrometry for Shotgun Proteomics

Nakamura, Tatsuji, Kuromitsu, Junro, Oda, Yoshiya

Journal:

Journal of Proteome Research

Year:

2008

Language:

english

File:

PDF, 1.17 MB

english, 2008

30

Mass spectrometry-based quantitative proteomics

Nakamura, Tatsuji, Oda, Yoshiya

Journal:

Biotechnology and Genetic Engineering Reviews

Year:

2007

Language:

english

File:

PDF, 199 KB

english, 2007

31

Petrological and geochemical evolution of the Tolbachik volcanic massif, Kamchatka, Russia

Churikova, Tatiana G., Gordeychik, Boris N., Iwamori, Hikaru, Nakamura, Hitomi, Ishizuka, Osamu, Nishizawa, Tatsuji, Haraguchi, Satoru, Miyazaki, Takashi, Vaglarov, Bogdan S.

Journal:

Journal of Volcanology and Geothermal Research

Year:

2015

Language:

english

File:

PDF, 4.17 MB

english, 2015

32

A Vacuolar-Type H⁺ ATPase in a Nonvacuolar Organelle Is Required for the Sorting of Soluble Vacuolar Protein Precursors in Tobacco Cells

Ken Matsuoka, Tatsuji Higuchi, Masayoshi Maeshima and Kenzo Nakamura

Journal:

Year:

1997

Language:

english

File:

PDF, 2.87 MB

english, 1997

33

Staining for Nerve Fiber and Cholinesterase Activity in Fresh Frozen Sections

Namba, Tatsuji, Nakamura, Toshio, Grob, David

Journal:

American Journal of Clinical Pathology

Year:

1967

Language:

english

File:

PDF, 1.22 MB

english, 1967

34

Molecular cloning and characterization of a novel dual-specificity protein phosphatase possibly involved in spermatogenesis

NAKAMURA, Koji, SHIMA, Hiroshi, WATANABE, Masahiko, HANEJI, Tatsuji, KIKUCHI, Kunimi

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 230 KB

english, 1999

35

Molecular cloning and characterization of a novel dual-specificity protein phosphatase possibly involved in spermatogenesis

NAKAMURA, Koji, SHIMA, Hiroshi, WATANABE, Masahiko, HANEJI, Tatsuji, KIKUCHI, Kunimi

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 230 KB

english, 1999

36

Studies of Antibody against Shigella in Bacillary Dysentery Patients and Carriers

MIYATA, Yoshihito, KOBAYASHI, Kazuhiro, KITAURA, Toshiyuki, HIRAKATA, Tatsuji, NAKAMURA, Minoru, SUGIYAMA, Shigehiko

Journal:

Kansenshogaku zasshi

Year:

1970

File:

PDF, 1.05 MB

1970

37

Documents for Clinical Trials of New Drugs: Results of Their Reviews prior to Submissions to IRB

TAKAYANAGI, Risa, YAMADA, Yasuhiko, WATANABE, Kaori, NAKAMURA, Hitoshi, OMATA, Masao, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2003

File:

PDF, 444 KB

2003

38

Effect of Mouth Wash on the Removing Fluticasone Propionate Delivered by Dry Powder Inhaler in Mouth.

YOKOYAMA, Haruko, YAMADA, Yasuhiko, YAMAMURA, Yoshikazu, NAKAMURA, Hitoshi, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2001

File:

PDF, 318 KB

2001

39

The Roles of Pharmacists on Prior Review of Clinical Trials.

TAKAYANAGI, Risa, YAMADA, Yasuhiko, ITO, Kaori, NAKAMURA, Hitoshi, SATO, Hitoshi, KIMURA, Kenjiro, OMATA, Masao, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2001

Language:

english

File:

PDF, 2.68 MB

english, 2001

40

The Effects of Indomethacin Spray on the Pain of Stomatitis in the Patients for Hematopoietic Stem Cell Transplantation

NAKAMURA, Takako, AOYAMA, Takao, YANAGIHARA, Yoshitsugu, YAMADA, Yasuhiko, MIYOSHI, Akemi, KANDA, Yoshinobu, HIRAI, Hisamaru, FURUKAWA, Toshirou, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2003

Language:

english

File:

PDF, 821 KB

english, 2003

41

The Construction and Evaluation of the Preventing Method for the Input Mischoice in a Prescription Order Entry System. Usefulness of a Three-Character Input and a Warning Screen Display System.

WATANABE, Megumi, SUGIURA, Munetoshi, SEINO, Toshikazu, MITSUNAGA, Yoshiharu, NAKAMURA, Hitoshi, YAMADA, Yasuhiko, TSUCHIYA, Fumito, OHE, Kazuhiko, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2002

Language:

english

File:

PDF, 3.04 MB

english, 2002

42

Creation and Usefulness of the “Drug Information Card” for Support of Dispensing

KAMATA, Shinobu, NEGISHI, Etsuko, OGATA, Akiko, NAKAJIMA, Katsuyoshi, ORII, Takao, NAKAMURA, Hitoshi, YAMADA, Yasuhiko, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2003

File:

PDF, 1.94 MB

2003

43

Effect of Mixing Method on the Mixing Degree during the Preparation of Triturations

NAKAMURA, Hitoshi, YANAGIHARA, Yoshitsugu, SEKIGUCHI, Hiroko, KOMADA, Fusao, KAWABATA, Haruno, OHTANI, Michiteru, SAITOH, Yukiya, KARIYA, Satoru, SUZUKI, Hiroshi, UCHINO, Katsuyoshi, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2004

Language:

english

File:

PDF, 284 KB

english, 2004

44

Development and Evaluation of Pharmaceutical Services in the ICU/CCU by Medical Staffs

MIYAZAKI, Norio, SEKINE, Yuko, AOYAMA, Takao, YASUNO, Nobuhiro, NAKAMURA, Hitoshi, YAMADA, Yasuhiko, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2004

Language:

english

File:

PDF, 612 KB

english, 2004

45

Effect of Particle Size on Mixing Degree in Dispensation

NAKAMURA, Hitoshi, YANAGIHARA, Yoshitsugu, SEKIGUCHI, Hiroko, OHTANI, Michiteru, KARIYA, Satoru, UCHINO, Katsuyoshi, SUZUKI, Hiroshi, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2004

Language:

english

File:

PDF, 232 KB

english, 2004

46

Analysis of Information Submitted by Clinical Trial Sponsors regarding the Safety of Investigational Drugs

TAKAYANAGI, Risa, NAKAMURA, Yuko, NAKAJIMA, Yuko, SHIMIZU, Akemi, NAKAMURA, Hitoshi, YAMADA, Yasuhiko, SUZUKI, Hiroshi, ARAKAWA, Yoshihiro, OMATA, Masao, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2004

Language:

english

File:

PDF, 296 KB

english, 2004

47

Pharmaceutical Investigation of Vancomycin Hydrochloride Eye Drops and Their Topical Application to MRSA Eye Infection.

ITOH, Mizuki, AOYAMA, Takao, IEMOTO, Akiko, NAKAJIMA, Katsuyoshi, AMANO, Shiro, NAKAMURA, Hitoshi, SATO, Hitoshi, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2001

Language:

english

File:

PDF, 1.91 MB

english, 2001

48

Items of Concern Associated with Source Document Verification of Clinical Trials for New Drugs

TAKAYANAGI, Risa, WATANABE, Kaori, NAKAHARA, Ayako, NAKAMURA, Hitoshi, YAMADA, Yasuhiko, SUZUKI, Hiroshi, ARAKAWA, Yoshihiro, OMATA, Masao, IGA, Tatsuji

Journal:

YAKUGAKU ZASSHI

Year:

2004

Language:

english

File:

PDF, 211 KB

english, 2004

49

Prediction of Therapeutic Doses of Beta-Adrenergic Receptor Blocking Agents Based on Quantitative Structure-Pharmacokinetic/Pharmacodynamic Relationship.

YAMADA, Yasuhiko, ITO, Kiyomi, NAKAMURA, Kouichi, SAWADA, Yasufumi, IGA, Tatsuji

Journal:

Biological & Pharmaceutical Bulletin

Year:

1993

File:

PDF, 1.17 MB

1993

50

Measurement of Area of Surplus X-ray Radiation by Dose-area Product Meter at Image Intensifier in Angiography X-ray Units

Seguchi, Shigenobu, Saijou, Takaya, Nagao, Tatsuji, Ishikawa, Yoshinobu, Mizuno, Shouta, Nakamura, Akirou

Journal:

Japanese Journal of Radiological Technology

Year:

2006

File:

PDF, 248 KB

2006

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